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Fumarate reductase is the enzyme that converts fumarate to succinate, and is important in microbial metabolism as a part of anaerobic respiration. Succinate + acceptor <=> fumarate + reduced acceptor In other words, fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalysed by the related complex II of the respiratory chain (succinate dehydrogenase). Fumarate reductase complex includes four subunits.〔http://www.sciencemag.org/content/284/5422/1961〕 Subunit A contains the site of fumarate reduction and a covalently bound flavin adenine dinucleotide prosthetic group. Subunit B contains three iron-sulphur centres. The menaquinol-oxidizing subunit C consists of five membrane-spanning, primarily helical segments and binds two haem b molecules.〔 The D subunit may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. ==See also== * Succinate dehydrogenase 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「fumarate reductase」の詳細全文を読む スポンサード リンク
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